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HHS Says Trans Treatments Based on Weak Evidence
“When medical interventions pose unnecessary, disproportionate risks of harm, healthcare providers should refuse to offer them even when they are preferred, requested, or demanded by patients.”
– U.S. Department of Health and Human Services, May 1, 2025
In May of 2025, the U.S. Department of Health and Human Services (HHS) issued a 409-page comprehensive review of the evidence and “best practices” of current transgender medical treatments for minor children.
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The review is titled Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices, and it’s a new truth-telling tool to combat the lies of the mainstream medical community. The review highlights a growing body of evidence pointing to significant risks—including irreversible harms such as infertility—while finding very weak evidence of benefit.
When releasing their review, HHS boldly declared…. “Despite increasing pressure to promote these drastic medical interventions for our nation’s youth, the review makes clear: the science and evidence do not support their use, and the risks cannot be ignored”.
A Sharp Rebuke to “Standard Practice”
HHS’s conclusions are a sharp rebuke to the World Professional Association for Transgender Health (WPATH) and The Endocrine Society, who created the standard treatment of what is deceptively called “gender-affirming care.” This care includes social affirmation of a child’s self-reported identity; puberty blockers to prevent the onset of puberty; cross-sex hormones; and genital surgeries, as well as mastectomies.
WPATH describes itself as an “interdisciplinary professional and educational organization devoted to transgender health”. They claim their standards of care (SOC) express “professional consensus” on how to treat people with gender dysphoria. Yet, WPATH is not strictly a medical organization comprised of medical professionals. Instead, a significant number of its membership are activists.
Yet WPATH’s influence shapes the policies and guidance of nearly every major medical association in the U.S. WPATH’s activist-driven guidelines are packaged and passed off as “settled science,” leading to a false sense of a medical consensus among so-called experts and their organizations. WPATH is one of the strongest voices trying to normalize radical medical interventions on children
Lies Exposed
WPATH’s medical guidelines for transgender care are followed by the American Medical Association and the American Psychological Association, which promote K-12 transgender treatments, denounce child protection laws, and urge insurance companies to cover these treatments.
In opposing state bans on transgender treatments, WPATH declared, “the benefits that these medically necessary interventions have for the overwhelming majority of youth … are well-documented.”
That is a lie, and HHS decisively called them on it.
Conflicting Studies Deliberately Suppressed
After reviewing WPATH’s international guidelines for medical intervention, HHS determined that they “lack rigor and transparency,” and alleged WPATH purposefully suppressed reviews that undermine their chosen approach.
Other studies are being suppressed as well. For instance, a prominent doctor and trans rights advocate, Dr. Johanna Olson-Kennedy, admitted she deliberately withheld publication of a $10 million taxpayer-funded study on the effect of puberty blockers on American children, after finding no evidence that they improve patients’ mental health. She worried that the study could one day be used in court against the use of puberty blockers.
HHS also found that medical and mental health associations stifled debate and suppressed dissent among their members.
Transgender advocates and activists appear to be in opposition to the tried-and-true scientific method. You create a hypothesis. You do research. You conduct clinical studies. You disclose your results even if they disprove your hypothesis. You report what you’ve learned. Simple.
While America’s medical establishments continue to promote these drastic medical interventions on children, HHS is clear: “the science and evidence do not support their use, and the risks cannot be ignored.”
The Polarizing Issue of our Time?
Sadly, discussions surrounding the medical transition of children go far beyond scientific debate. For the trans activists and liberal politicians, transgender care is the “civil rights” issue of our time. They stubbornly cling to and demand medical interventions for themselves and others to live their “true” selves as the opposite sex while ignoring the growing body of evidence of serious and irreparable harm caused by these unnatural medical interventions.
For the rest of us, pediatric transgender treatment is the greatest medical scandal of our time, based on deceit and lies, and a demonic rebellion against God, the Creator. Thankfully, HHS’s eye-opening review of the evidence-backed science of these treatments reveals the very shaky and crumbling foundations of this horrific scam and attack on children.
That’s because HHS’s review evaluating the benefits and harms to children claiming to suffer from gender dysphoria found the quality of the scientific evidence to be “very low,” and the potential for irreversible harm to be “very high”.
The review went on to say, “The beneficial effects reported in the literature are likely to differ substantially from the true effects of the interventions.” In other words, actual results do not live up to the hype and fraudulent basis of WPATH’s treatments.
As regards the harm of these transition treatments, the review listed the following risks: infertility/sterility, sexual dysfunction, impaired bone density accrual, adverse cognitive impacts, cardiovascular disease and metabolic disorders, psychiatric disorders, surgical complications, and regret.
Thousands of American children and adolescents have received these medical interventions to supposedly transition to the opposite sex.
The Trump Administration is unmistakably saying…no more.
“Parents who are desperate to help their confused, frustrated children have understandably turned to medical professionals for help,” Attorney General Pam Bondi wrote in a memo calling for gender treatments for minors to be investigated and prosecuted as genital mutilation. “Unfortunately, those parents have been betrayed by politically captured profiteers at every step.”
Truth is Revealed
The real harm and medical risk of these trans treatments are often hidden from parents. Instead, parents and their children are told these drastic and permanent medical interventions are necessary, even “life-saving”.
The pediatrician’s sadistic appeal to worried parents is often, “Would you rather have a dead son or a live daughter?”, warning of their child’s potential suicide if they don’t conform to “accepted” trans treatments. The American Academy of Pediatrics says transgender care is “vital” and reduces the risk of suicide.
But there’s no statistical support for increased suicides among those with gender dysphoria. In fact, research shows that those who transition are 19 times more likely to commit suicide than the general population. None of this is reported by Big Med or Big Media.
You may wonder why doctors with years of medical training fall in line with WPATH’s guidance, which to the rest of us sounds crazy and extreme, and flies in the face of science and biology.
It appears that most doctors will follow the direction of mainstream medicine because there is a massive risk in breaking away from “settled science.” We saw it during the COVID pandemic. Doctors who speak up risk being professionally ostracized. They risk being fired or having their hospital privileges revoked, or their licenses and credentials taken away by state medical boards.
Another reason why doctors, hospitals, and other medical professionals remain quiet could be the huge profits to be made from chemically and surgically sterilizing children. Hospitals have made well over $120 million performing the surgeries. Planned Parenthood is a leading supplier of the drugs, raking in millions more.
Is the medical establishment deliberately ignoring evidence-based science and studies to line their pockets?
Health Assessments Minimized
Perhaps the most tragic aspect of the transgender craze is the minimal assessment by the medical profession of the children who claim to be confused about their gender. Instead of a thoughtful, cautious approach, children are rushed into treatment.
HHS reported “The ‘gender-affirming’ model of care, as practiced in U.S. clinics, is characterized by a child-led process in which comprehensive mental health assessments are often minimized or omitted, and the patient’s ’embodiment goals’ serve as the primary guide for treatment decisions. In some of the nation’s leading pediatric gender clinics, assessments are conducted in a single session lasting two hours.”
This is shocking news. Just two hours of assessment is all that is needed to begin dangerous, harmful, and irreparable treatments on children with life-long consequences.
What young child or teenager, who most likely has yet to take a high school biology class, can even comprehend permanent health risks as severe as infertility and sexual dysfunction for the rest of their lives? Are doctors even explaining the risks to them and their parents?
WPATH has purposefully misled the public by acknowledging in leaked videotapes that children are unable to comprehend the powerful and life-altering effects of hormone therapy and the loss of their fertility. WPATH also privately admits that parents are not literate enough in these health hormones to understand the true effects of these treatments.
In an Identity Evolution Workshop, WPATH panel members admitted to “the impossibility of getting proper informed consent for hormonal interventions from their young patients”, even going so far as to say, “adult patients often have very little medical understanding of the effects of these interventions.” WPATH will not discuss these concerns publicly.
HHS Hits Back on Puberty Blockers
The HHS review scrutinizes puberty blockers, which are promoted by WPATH, activists, and America’s top medical associations as safe, temporary, and fully reversible. The language WPATH uses to describe puberty blockers is truly diabolical.
WPATH refers to puberty blockers as a “pause button,” giving children “time to explore” their gender identity without the pressure of their natural physical development in the sex God created them to be.
HHS strongly disagrees with WPATH’s position. The review cited studies that show over 90% of children who begin puberty blockers go on to the more invasive cross sex hormones. The next step is life-altering surgery.
Yet HHS found in their exhaustive review that children who do not take these drugs will grow out of their gender dysphoria. With evidence such as this, why isn’t a ‘let’s wait-and-see’ attitude acceptable and prudent?
Because puberty blockers stop the development of sexual organs, affect bone density and brain development, their effects are not reversible. The HHS Review makes clear that the long-term effects of puberty blockers and other medical interventions for gender dysphoria remain largely unknown.
The UK’s National Health Service stopped puberty blockers for children after the Cass Report was released. That report stated, “For most young people, a medical pathway will not be the best way to manage their gender-related distress.” Another conclusion ignored by transgender advocates and activists.
Other European countries are taking a more cautious approach as well, banning puberty blockers on minors and developing treatments in line with clinical evidence, citing uncertain evidence of the benefits and risks.
Let’s pray that the HHS Review will open the eyes of the medical establishment here in America to ban these harmful drugs and surgeries.
HHS Calls for Psychotherapy
The HHS review laments the lack of research on psychotherapeutic approaches to helping children cope with gender dysphoria. HHS concludes that this lack is due to the mischaracterization of such non-invasive therapeutic approaches as “conversion therapy”, which is banned in nearly half of the states.
The Supreme Court has agreed to hear a case, Chiles v. Salazar, in October 2025 on the constitutionality of Colorado’s ban on conversion therapy as a violation of the First Amendment regarding free speech and free exercise of religion. Let’s pray that the HHS Review will be considered in the justices’ decision, which will be handed down in the summer of 2026.
The HHS Review points out that the shocking rise in gender dysphoria has occurred against a broader mental health crisis affecting young people, while reinforcing the fact that there is no evidence of a heightened risk of suicide in gender confused children.
HHS supports “psychotherapy as a noninvasive alternative to endocrine and surgical interventions for the treatment of pediatric gender dysphoria.” HHS also found no evidence of adverse effects of psychotherapy in this context.
Review Criticized by the Usual Suspects
The HHS Review has been heavily criticized by LGBTQ+ activists, along with nearly every major medical association in the U.S. No surprise there.
They prefer to stick with the shaky and deceptive guidelines of WPATH and repeat their mantra, calling transgender treatment for children “well-established and widely accepted based on decades of scientific study and clinical experience.”
WPATH reiterated its position that “gender-affirming care is backed by rigorous research and expert consensus.”
HHS disproves these positions based on a comprehensive, evidence-backed scientific review.
The Impact of the HHS Review
While the review does not recommend specific policy changes, it does offer lawmakers, regulators, judges and justices a new scientific foundation to revisit medical guidelines.
The HHS Review also strengthens the Centers for Medicare and Medicaid Services (CMS) directive that states not to use Medicaid funds for gender reassignment surgeries or hormone treatments. Unfortunately, the Senate Parliamentarian removed the national ban on Medicaid funds being used for transgender treatments in the Big, Beautiful Bill.
At least 10 states have introduced legislation to ban Medicaid coverage for this. With the strong scientific rebuke outlined in the HHS Review, let’s pray more states and Congress will be emboldened to say weak and unproven transgender care is not a good use of Medicaid funds and pass more bans.
The HHS Review could also be used as evidence to strengthen the growing number of legal suits brought by de-transitioners, such as Chloe Cole. These young people feel they were misled and pushed into these irreversible treatments with very little assessment of any emotional or psychological reasons for their temporary confusion. They want these doctors, hospitals, and clinics held responsible.
The HHS Review could give the courts a legal framework to rule that WPATH’s standard of care guidelines are nothing but experimental medicine and not based on scientific evidence.
The tenet of the Hippocratic Oath is “Do No Harm.” HHS confirms that the transgender care being pushed on America’s children does nothing BUT cause harm.
It has to stop… and thanks to unrelenting pressure by the Trump Administration, including the HHS Review, major hospitals across the country are stopping trans treatments on minors. Prominent hospitals and medical providers in Deep Blue California, Deep Blue Chicago, Pittsburgh, and Deep Blue DC announced they would no longer be offering transgender care.
In June, the Supreme Court in U.S. v. Skrmetti ruled that state bans on transgender care for minors are constitutional. More than half of the states have such bans.
The tide appears to be turning, but we must continue praying to eradicate this demonic attack on our children once and for all. Let’s pray for common sense and sanity based on biological facts and scientific evidence to return to the practice of medicine.
“Our duty is to protect our nation’s children, not expose them to unproven and irreversible medical interventions,” said NIH Director Dr. Jay Bhattacharya. “We must follow the gold standard of science, not activist agendas.” Amen.
Let’s Pray
Dear Heavenly Father, we thank You for the truth being revealed about the weakness of scientific evidence and the lies of “settled” transgender care being exposed. We pray that HHS’s comprehensive review changes hearts and minds among the medical community, media, activists, and lawyers to end these harmful, permanent interventions that are destroying the lives and health of our children. Lord, restrain the corrupters of Your Word and all the enemies of Your sovereign creation covenant that You created two sexes – male and female. “Make them bear their guilt and fall by their own counsels.” (Psalm 5:10 ESV)
Lord, we ask for Your protection, love, and mercy to fall upon every child and their parents who are suffering through this demonic deception. Grant them wisdom and discernment not to fall for the lies but to seek Your counsel and refuge. Heal them from all physical and emotional harm from the damage inflicted upon them by misguided and untruthful experts. Give justice to those who are seeking through the courts to hold the evildoers accountable.
“But let all who take refuge in you rejoice; let them ever sing for joy, and spread your protection over them, that those who love your name may exult in you. For you bless the righteous, O Lord; you cover them with favor as with a shield.” (Psalm 5:11-12 ESV)
May Your Name, Lord, King of the Universe, Your truth and glory be exalted in the nation. In Jesus’ Name, Amen.
Add your own prayers in the comments below.
Belinda Brewster analyzes cultural, political, and world events from a biblical worldview. Belinda’s passion is to equip, support, and encourage parents and grandparents who are courageously battling against the spiritual and cultural forces impacting children and grandchildren. Photo Credit: Official White House Photo by Joyce N. Boghosian.
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Comments
Thank you, Belinda, for this article. I am praying with you for the protection of our youth and the revealing of the corruption.
How many father we come to you in the name of Jesus. To continue shed light against the forces of evil. Let not the enemy have any more of these children but break every stronghold in the name of Jesus. May they all know the truth and the truth system free that they are made in the image of you oh God. Turn the hearts towards you so they can feel your love and support and to become who you have made them to be. We come against every confusion and self hate in the name of Jesus. May there be a great pushback against this ideology of gender dysphoria. Please give secretary Kennedy great wisdom to come against all matter of evil thoughts and intents. Put a stop to this madness and bring a solution where the youth find freedom from the grips of the devil. I pray for all the youth to be protected against the plans of the enemy. In the name of Jesus we pray and thank you Lord God
Thank you, Belinda! YHVH, the battle continues in this war, but we are so thankful for every divine reversal You provide. We see this as a welcome answer to our prayers and intercession. As Your soldiers, we have been given all we need to wage warfare against Your enemies – the enemies of righteousness and justice and truth. May we take our marching orders from You, and trust Your provision – even when we tire. I often think of a scene in the movie Gettysburg when thinking about spiritual warfare. Chamberlin and his unit have already faced fierce battles, and in the very place they are sent to receive some well-earned relief, they are attacked again. Out of ammo, exhausted, told to hold the line at any cost, and facing yet another surge of the enemy – he gives the astounding order to “Fix bayonets and charge!” It worked!! Intercession is a good thing, so let us not grow weary.
Gal 6:9 So let us not grow weary of doing what is good; for if we don’t give up, we will in due time reap the harvest.
Thank you, Sovereign Lord Jesus, for inspiring and convicting Belinda to expose to the Light of Your Gospel one of satan’s most heinous lies, permeating our country. The Enemy’s full frontal attack against our children is his sharpest weapon wielded against God, the Creator, the author of human life from the moment of conception. Satan’s ersatz attempt to challenge God’s Creation mandate in designing humans as only male and female in His Image, is an abomination. Lord, convict your Intercessors to powerfully stand in the gap with mighty prayer against this demonic sin. Open the mouths of your servants in pulpits to denounce it. May the voice of the faithful remnant of your Church resound across the Nation to drown out the lies of the Enemy and the voices of those who have succeeded in deceiving the whole country into protecting satan’s unchallenged right to ‘play god’ at the expense of innocent lives. By the power of Your Shed Blood and Holy Spirit, Amen.
Thank you, Belinda, for a strong, well-written expose of these issues. May Holy Spirit move among believers to strongly and prayerfully stand against this destructive force moving against the children who are the future of our nation.
Thank You Lord that the truth is now being brought to the Light!